Merck 102431.2500 Chloroform EMPROVE

Ürün Özellikleri

CAS #	EC Number	Hill Formula	Chemical Formula	Molar Mass
67-66-3	200-663-8	CHCl₃	CHCl₃	119.38 g/mol

Description
Catalogue Number	102431
Synonyms	TCM, Trichloromethane, Methane trichloride, Methyl trichloride

Merck 102431.2500 | Chloroform suitable for use as excipient 2,5L

Product Information
CAS number	67-66-3
EC index number	602-006-00-4
EC number	200-663-8
Hill Formula	CHCl₃
Chemical formula	CHCl₃
Molar Mass	119.38 g/mol
HS Code	2903 13 00
Structure formula Image

Physicochemical Information
Boiling point	61 °C (1013 hPa)
Density	1.48 g/cm3 (20 °C)
Melting Point	-63 °C
Vapor pressure	211 hPa (20 °C)
Refractive Index	1.45
Solubility	8 g/l (20 °C)

Toxicological Information
LD 50 oral	LD50 Rat 695 mg/kg
LD 50 dermal	LD50 Rabbit > 3980 mg/kg

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H331: Toxic if inhaled. H351: Suspected of causing cancer. H361d: Suspected of damaging the unborn child. H372: Causes damage to organs through prolonged or repeated exposure.
Precautionary Statement(s)	P281: Use personal protective equipment as required. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P310: IF exposed or concerned: immediately call a POISON CENTER or doctor/ physician.
Signal Word	Danger
RTECS	FS9100000
Storage class	6.1 D Non combustible, acute toxicity cat. 3 / toxic or substances with chronic effects
WGK	WGK 3 highly water endangering
Disposal	2 Organic halogenated solvents and solutions of organic halogen-containing substances: For strongly contaminated or mixed halogenated solvents container B: Caution: Do not use aluminium containers; in addition, in the case of water-containing chlorinated waste materials do not use stainless-steel containers (danger of leaks caused by corrosion).

Safety Information
Hazard Symbols	Harmful
Categories of danger	harmful, irritant, carcinogenic, toxic for reproduction
R Phrase	R 20/22-36/38-40-48/20-63 Harmful by inhalation and if swallowed.Irritating to eyes and skin.Limited evidence of a carcinogenic effect.Harmful: danger of serious damage to health by prolonged exposure through inhalation.Possible risk of harm to the unborn child.
S Phrase	S 36/37 Wear suitable protective clothing and gloves.

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 1888 , 6.1, III
Declaration (transport by air) IATA-DGR	UN 1888 , 6.1, III
Declaration (transport by sea) IMDG-Code	UN 1888 , 6.1, III, Segregation Group: 10 (Liquid halogenated hydrocarbons)

Specifications
Specifications
Purity (GC)	99.0 – 99.4 % (w/w)
Identity (IR)	conforms
Acidity or alkalinity	conforms
Density (d 20 °C/ 4 °C)	1.474 – 1.479
Density (d 20 °C/20 °C)	1.479 – 1.482
Boiling range (60-62°C)	≥ 95 % (v/v)
Chloride (Cl)	conforms
Free chlorine (as Cl)	conforms
Ethanol (GC)	1.0 – 2.0 % (v/v)
Related substances (GC)	≤ 1.0 % (v/v)
Bromochloromethane (GC)	≤ 0.01 %
1,2-Dichloroethene (GC)	≤ 0.05 %
Dichloromethane (GC)	≤ 0.01 %
Carbon tetrachloride (GC)	≤ 0.01 %
1,1,2-Trichloroethene (GC)	≤ 0.01 %
Other residual solvents (ICH Q3C)	excluded by manufacturing process
Aldehydes	conforms
Foreign chlorine compounds	conforms
Matter discoloured by H₂SO₄	≤ 10 Hazen
Evaporation residue	≤ 0.0010 %
Water	≤ 0.10 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present. Stabilized with 1,0 – 2,0% V/V ethanol Conforms to BP

67-66-3, trichloromethane, tcm metan triklorür, metil triklorür, kloroform, merck solvent

Chloroform EMPROVE ESSENTIAL suitable for use as excipient EMPROVE® exp

M102431.2500

1.02431.2500

1024312500

Kloroform EMPROVE ESSENTIAL yardımcı madde olarak kullanıma uygun EMPROVE® exp

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